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Clinical observational studies and meta-analyses have shown that metabolic indicators, such as BMI and body fat percentage, can be improved in patients with prolactinomas treated with dopamine agonists ( In addition, clinical observational studies suggest that weight-loss intervention is associated with a decrease in circulating prolactin levels in individuals with hyperprolactinemia

These free thiols, which indicate systemic oxidative stress, showed a strong correlation with endoscopic disease activity and were more effective in distinguishing disease severity than fecal calprotectin levels

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